No-Doz
A caffeine-based medication designed to help keep you awake if you are feeling tired or drowsy.
Mentioned in No Not Now on Thing-Fish: "Wooo, looka-dat! A big ol' truck, 'n a box uh NODOZ, 'n ovuh deah, a greazy ol' dinuh where yo rubber bitch kin reassume part-time employment in her former professium: slingin' hash in de directium o' de blue-collar community!"
One of Frank Zappa's favorite songs, Bob Dylan's "Subterranean Homesick Blues", includes the line, "Don't try No-Doz".